|
|
|
| Registros recuperados: 13 | |
|
|
| Colombo,Arnaldo Lopes; Guimarães,Thaís; Camargo,Luis Fernando Aranha; Richtmann,Rosana; Queiroz-Telles,Flavio de; Salles,Mauro José Costa; Cunha,Clóvis Arns da; Yasuda,Maria Aparecida Shikanai; Moretti,Maria Luiza; Nucci,Marcio. |
| Candida infections account for 80% of all fungal infections in the hospital environment, including bloodstream, urinary tract and surgical site infections. Bloodstream infections are now a major challenge for tertiary hospitals worldwide due to their high prevalence and mortality rates. The incidence of candidemia in tertiary public hospitals in Brazil is approximately 2.5 cases per 1000 hospital admissions. Due to the importance of this infection, the authors provide a review of the diversity of the genus Candida and its clinical relevance, the therapeutic options and discuss the treatment of major infections caused by Candida. Each topography is discussed with regard to epidemiological, clinical and laboratory diagnostic and therapeutic recommendations... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidiasis; Candidemia; Treatment; Antifungals. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300001 |
| |
|
|
| Hinrichsen,Sylvia Lemos; Falcão,Érica; Vilella,Tatiana Aguiar Santos; Rêgo,Leandro; Lira,Conceição; Almeida,Luciano; Martins,Mízia; Araújo,Carmem; Duarte,Marcelo; Lopes,Geraldo. |
| Candida is an opportunistic pathogen that affects highrisk patients who are either immunocompromised or critically ill and is associated with almost 80% of all nosocomial fungal infections, representing the major cause of fungemia with high mortality rates (40%). Candida albicans is the main cause of candidemia and among the non-albicans species C. parapsilosis, C. glabrata and C. tropicalis are the most frequent agents. The aim of this study was to evaluate the distribution of Candida species in two tertiary hospitals in Recife, Northeastern Brazil. It began by surveying all positive Candida cultures processed by the microbiology laboratory from September 2003 to September 2006. The cultures, originated from various types of biological material (blood,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida; Candidemia; Candida isolates. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000200021 |
| |
|
|
| Mondelli,AL; Niéro-Melo,L; Bagagli,E; Camargo,CH; Bruder-Nascimento,A; Sugizaki,MF; Carneiro,MV; Villas Boas,PJF. |
| Yeasts are becoming a common cause of nosocomial fungal infections that affect immunocompromised patients. Such infections can evolve into sepsis, whose mortality rate is high. This study aimed to evaluate the viability of Candida species identification by the automated system Vitek-Biomerieux (Durham, USA). Ninety-eight medical charts referencing the Candida spp. samples available for the study were retrospectively analyzed. The system Vitek-Biomerieux with Candida identification card is recommended for laboratory routine use and presents 80.6% agreement with the reference method. By separate analysis of species, 13.5% of C. parapsilosis samples differed from the reference method, while the Vitek system wrongly identified them as C. tropicalis, C.... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Candidemia; Candida spp.; Identification; Automated identification. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300011 |
| |
|
|
| Motta,Adriana Lopes; Almeida,Gisele Madeira Duboc de; Almeida Júnior,João Nóbrega de; Burattini,Marcelo Nascimento; Rossi,Flávia. |
| INTRODUCTION: Although the spectrum of fungi causing bloodstream fungal infections continues to expand, Candida spp. remains responsible for the majority of these cases. OBJECTIVE: The purpose of this study was to characterize the candidemia epidemiology, species distribution and antifungal susceptibility patterns at a Brazilian tertiary teaching public hospital with 2,500 beds. METHODS: Records from the microbiology laboratory were used to identify patients with positive blood cultures during 2006. The in vitro activity of amphotericin B, caspofungin, itraconazole, fluconazole, voricanozole, and posaconazole were determined using the Etest method. RESULTS: One hundred and thirty-six cases of candidemia were identified and 100 strains were available for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidemia; Candida spp; Susceptibility testing; Candida epidemiology; Candida Etest; Antifungal susceptibility profile; Candida antifungal agents; Azoles. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500004 |
| |
|
|
| Mondelli,AL; Niéro-Melo,L; Bagagli,E; Camargo,CH; Bruder-Nascimento,A; Sugizaki,MF; Carneiro,MV; Villas Boas,PJF. |
| Yeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were: antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were: C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidemia; Mortality; Associated factors; Candida albicans. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000200015 |
| |
|
|
| Cortés,Jorge Alberto; Reyes,Patricia; Gómez,Carlos Hernando; Cuervo,Sonia Isabel; Rivas,Pilar; Casas,Christian A.; Sánchez,Ricardo. |
| Background:Bloodstream infection by Candida species has a high mortality in Latin American countries. The aim of this study was to describe the characteristics of patients with documented bloodstream infections caused by Candida species in third level hospitals and determine the risk factors for in-hospital-mortality.Methods:Patients from seven tertiary-care hospitals in Bogotá, Colombia, with isolation of a Candida species from a blood culture were followed prospectively from March 2008 to March 2009. Epidemiologic information, risk factors, and mortality were prospectively collected. Isolates were sent to a reference center, and fluconazole susceptibility was tested by agar-based E-test. The results of susceptibility were compared by using 2008 and 2012... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida; Candidemia; Candidemia/epidemiology; Candidemia/mortality; Candidemia/therapy; Colombia; Fluconazole. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600631 |
| |
|
| |
|
|
| Dizbay,Murat; Kalkanci,Ayse; Sezer,Busra Ergut; Aktas,Firdevs; Aydogan,Sibel; Fidan,Isil; Kustimur,Semra; Sugita,Takashi. |
| We investigated a nosocomial cluster of four Candida parapsilosis fungemia episodes that occurred in a neurological intensive care unit over a two-week period. The four infected patients had received parenteral nutrition through central lines, and all four had catheter-related candidemia. All of the isolates were susceptible to all of the antifungals tested, including amphotericin B, fluconazole, voriconazole, and caspofungin. They had strictly related fingerprints, based on randomly amplified polymorphic DNA analysis. Additional DNA sequencing data revealed that they were same strain. Although no isolate of Candida parapsilosis was recovered from other clinical, surveillance, or environmental samples, nosocomial spread of this yeast ceased, following the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidemia; Candida parapsilosis; Nosocomial outbreak; Intensive care unit; RAPD; DNA sequencing. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500010 |
| |
|
|
| Aquino,Valério Rodrigues; Lunardi,Luciano W.; Goldani,Luciano Zubaran; Barth,Afonso Luis. |
| Bloodstream infections caused by yeast, Candida spp, are quite important clinically and epidemiologically due to a high mortality rate and an increasing number of non-albicans species with a more resistant (differentiated susceptibility) profile. We examined species prevalence and susceptibility profile for fluconazole and the risk for nosocomial infections by Candida spp at the Hospital de Clínicas de Porto Alegre, a general tertiary care hospital in southern Brazilian, through a retrospective study, beginning with positive cultures of hospitalized patients. The distribution by species in 131 documented episodes was as follows: Candida albicans (45%), C. parapsilosis (24.4%), C. tropicalis (15.3%), C. glabrata (6.9%), C. krusei (4.6%) and 3.8% other... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fluconazole; Candidemia; Risks; Southern Brazil. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500009 |
| |
|
| |
|
| |
|
|
| Colombo,Arnaldo L.; Janini,Mario; Salomão,Reinaldo; Medeiros,Eduardo A. S.; Wey,Sergio B.; Pignatari,Antonio C. C.. |
| Several epidemiological changes have occurred in the pattern of nosocomial and community acquired infectious diseases during the past 25 years. Social and demographic changes possibly related to this phenomenon include a rapid population growth, the increase in urban migration and movement across international borders by tourists and immigrants, alterations in the habitats of animals and arthropods that transmit disease, as well as the raise of patients with impaired host defense abilities. Continuous surveillance programs of emergent pathogens and antimicrobial resistance are warranted for detecting in real time new pathogens, as well as to characterize molecular mechanisms of resistance. In order to become more effective, surveillance programs of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Emerging infectious diseases; HIV; AIDS; Candidemia; Antimicrobial resistance; Bacteremia; Sepsis; Nosocomial infectious. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300020 |
| |
|
|
| Nucci,Marcio; Braga,Paula Rocha; Nouér,Simone A.; Anaissie,Elias. |
| ABSTRACT Background: The impact of central venous catheter (CVC) removal on the outcome of patients with candidemia is controversial, with studies reporting discrepant results depending on the time of CVC removal (early or any time during the course of candidemia). Objective: Evaluate the effect of time to CVC removal, early (within 48 h from the diagnosis of candidemia) vs. removal at any time during the course of candidemia, on the 30-day mortality. Methods: Retrospective cohort study of 285 patients with candidemia analyzing CVC removal within 48 h (first analysis) or at any time (second analysis). Results: A CVC was in place in 212 patients and was removed in 148 (69.8%), either early (88 patients, 41.5%) or late (60 patients, 28.3%). Overall, the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidemia; Central venous catheter; Mortality; Multivariate analysis; Candida. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600455 |
| |
| Registros recuperados: 13 | |
|
|
|
